I don't know if slowing down SkySafari is enough to make Polar Alignment work, or you need to turn SkySafari off completely.
But, using my mount simulator with ASIAIR, I have seen the 4 poll/sec from SkySafari confuses the heck out of ASIAIR with other things than Polar Alignment. Turning it down to 1 poll/sec or slower makes ASIAIR much happier (I may also have tested this during the days of the Raspberry Pi 3, and was even more processor constrained than today).
Remember that SkySafari does not talk to your mount. Except for perhaps some TCP/UDP implementations, only one program can be controlling the mount.
So, what ASIAIR does (for many, but not all mount models) is to open a proxy server. What this proxy server does is to make itself look like a mount to any third party program (like SkySafari). SkySafari talks to this proxy port and ASIAIR forwards the mount commands to the mount itself and then return the mount response back to the third party.
Now imagine ASIAIR is in the middle of something like sending slews or guide pulses, and SkySafari suddenly injects a poll (usually a RA-declination request), the response from the mount can be easily misrouted (unless ZWO has very carefully coded the proxy as a real router that knows about source and destinations).
Slowing down the polling can still cause a collision, but it may be lower probability.
Since SkySafari does not understand EQMOD (thay have promised that for at least 5 years now and still nothing), I think ZWO decided not to wait for SkySafari and actually also included translator to the proxy when EQMOD is selected in ASIAIR. When set to "EQMOD with SkySafari," ASIAIR's proxy looks like a LX200. It translates the LX200 commands from SkySafari to EQMOD API calls, and translate replies from the EQMOD driver back to LX200 replies. This is why when using "EQMOD With SkySafari," you need to set SkySafari up as an LX-200 mount.
All that said, I only use SkySafari for pre-planning the night's targets. I never connect SkySafari to ASIAIR, after my earlier experiments to study what it does to ASIAIR when I monitored the commands that is passed through to my mount simulator. You don't need SkySafari; it is just eye candy (which of course makes Facebook types happy).
Once ZWO finish adding their own planetarium program to the ASIAIR app, SkySafari will become even more obsolete.